Table 1.
MIC (mg/L)a | ||||
---|---|---|---|---|
Strain | β-Lactamase | Aztreonam | Nacubactam | Aztreonam/nacubactamb |
K. pneumoniae | ||||
ȃATCC BAA-2473 | NDM-1 | 256 | 256 | 1 |
ȃMSC 21664 | IMP-6, CTX-M-2 | 32 | 16 | 0.016 |
ȃMSC 21444 | OXA-48 | 512 | 2 | 1 |
MIC value is the median of technical replicates (n = 3).
MIC of nacubactam measured with a fixed aztreonam concentration of 4 mg/L.