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. 2022 Dec 19;21(4):374–385. doi: 10.1158/1541-7786.MCR-22-0474

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©2022 The Authors; Published by the American Association for Cancer Research

This open access article is distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0) license.

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Figure 3. The distinct signature landscape of PTs and matched BMs. A, The fraction of six substitution subtypes SNV in each group. B, Fractions of SBS signatures in each group. C, The average fraction difference of the top eight signatures in each group. — The distinct signature landscape of PTs and matched BMs. A, The fraction of six substitution subtypes SNV in each group. B, Fractions of SBS signatures in each group. C, The average fraction difference of the top eight signatures in each group.