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Apicidin increases the protein level of ADAM10 with an altered APP processing. (A and B) Representative Western blots of APP, ADAM10, BACE1, PSEN1, sAPPα, and sAPPβ in the hippocampus (A) and cortex (B) of WT and AD mice, in the absence or presence of apicidin, respectively. (C–O) Quantification of Western blots from the hippocampus (C–L) and cortex (E–O). Two‐way ANOVA with multiple comparisons test was used for all comparisons. The graphs represent mean ± SEM. *p < 0.05; n = 6.
