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. 2023 Mar 21;26(4):106460. doi: 10.1016/j.isci.2023.106460
REAGENT or RESOURCE SOURCE IDENTIFIER
Deposited data

Bgee Bastian et al., 202131 https://bgee.org/
Brenda Tissue Ontology Chang et al., 202127 https://www.brenda-enzymes.org/index.php
Cell Ontology Diehl et al., 201628 http://obofoundry.org/ontology/cl.html
Comparative Toxicogenomics Database (CTD) Davis et al., 201932 http://ctdbase.org/
ChEMBL Gaulton et al., 201242 https://www.ebi.ac.uk/chembl/
Chemical Entities of Biological Interest (ChEBI) de Matos et al., 201043 https://www.ebi.ac.uk/chebi/init.do
Drug Repurposing Knowledge Graph (DRKG) Ioannidis et al., 202039 https://github.com/gnn4dr/DRKG
Disease Ontology Schriml et al., 201229 https://disease-ontology.org/
DrugBank Wishart et al., 201833 https://go.drugbank.com/
Hetionet Himmelstein et al., 20174 https://github.com/hetio/hetionet
HUGO Gene Nomenclature Committee (HGNC) Braschi et al., 201941 https://www.genenames.org/
Integrated Dietary Supplement Knowledge Base (iDISK) Rizvi et al., 202040 https://conservancy.umn.edu/handle/11299/204783
Kyoto Encyclopedia of Genes and Genomes (KEGG) Kanehisa and Goto, 200034 https://www.kegg.jp/
Pharmacogenetics Knowledge Base (PharmGKB) Hewett et al., 200235 https://www.pharmgkb.org/
Reactome Fabregat et al., 201836 https://reactome.org/
Side effect resource (SIDER) Kuhn et al., 2016 http://sideeffects.embl.de/
TISSUE Palasca et al., 201838 https://tissues.jensenlab.org/
Uberon Mungall et al., 201230 https://www.ebi.ac.uk/ols/ontologies/uberon
Unified Medical Language System (UMLS) Bodenreider, 200487 https://www.nlm.nih.gov/research/umls/index.html
iBKH source files This paper https://github.com/wcm-wanglab/iBKH/tree/main/iBKH
iBKH portal This paper http://ibkh.ai/

Software and algorithms

Neo4j Neo4j, Inc. https://neo4j.com
Python Python Software Foundation https://www.python.org
Django Django Software Foundation https://www.djangoproject.com
neovis.js Neo4j Contrib https://github.com/neo4j-contrib/neovis.js
D3.js Mike Bostock https://d3js.org
DGL-KE (Deep Graph Library – Knowledge Graph Embedding) Zheng et al., 202026 https://github.com/awslabs/dgl-ke
iBKH construction and iBKH-based knowledge discovery This paper https://github.com/wcm-wanglab/iBKH