Table 3.

Literature on stem cell transplant in patients with thalassemia major

	No. of Patients	Conditioning regimen	Risk classification	Overall survival (%)	Thalassemia free survival (%)	Treatment related mortality (%)	aGVHD/cGVHD(%)
Our study	55	Flu/Bu/Cy/ATG	Class I (22)	100	54/55	Nil	7.2/7.2
			Class II (15)		( 98.10% )
			Class III (18)
Lucarelli et al. (1990)3	116	Bu/Cy	Class I (39)	94/80/61	NA	5.1/19.4/37.5	4.3/0.8
			Class II (36)
			Class III (24)
Sabloff et al. (2011)6	179	Bu/Cy/ATG	Low: 2%	5 Years	5 Years	3 Years	NA
			Intermediate: 42%	Intermediate risk: 91%	Intermediate risk: 88%	Intermediate risk: 5/75
			High: 36%	High risk: 64%	High risk: 62%	High risk: 23/64
Chandy et al. (2005)7	47	Bu/Cy	Class II-21	68%	NA	32%	30/NA
			Class III- 25
Bernardo et al. (2012)9	60	Thio/Treo/Flu	Low: 27	5 Years	5 Years	3 Years	14/1.7
			Intermediate:17	93%	84%	7%
			High: 4
			Adults: 12
Choudhary et al. (2013)10	28	Thio/Treo/Flu	Children:	3 Years	3 Years	3 Years	14/7.1
			Intermediate risk: 7	78.50%	71.40%	21.40%
			High risk: 21
Mathews et al. (2013)11	50	Thio/Treo/Flu	High risk	3 Years	3 Years	100 days	32/17
				86.60%	77.80%	13%
Di Bartolomeo et al. (2008)26	115	Bu/Cy	All categories	20 Years	20 Years	1 Year	37/17
				89.20%	85.70%	8.70%
Lawson et al. (2003)27	55	Bu/Cy/Flu	Low: 17	8 Years	8 Years	1 Year	31/14
			Intermediate: 27	94.50%	81.8	5.40%
			High: 11