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. Author manuscript; available in PMC: 2023 Apr 3.
Published in final edited form as: Cancer Lett. 2014 Apr 24;350(1-2):15–24. doi: 10.1016/j.canlet.2014.04.017

Fig. 4.

Fig. 4.

LRH1 promoted wound healing and sphere formation. (A) LRH1 accelerated wound healing of PC cell lines Capan-1 and AsPC-1. Compared to vector control, LRH1 stable expressing Capan-1 and AsPC-1 cells exhibited accelerated wound healing at 24 h. An increase in relative migration distance was present in LRH1 stable cells compared to vector control (**p < 0.01), (B) LRH1 stable overexpression promoted sphere formation in Capan-1 and AsPC-1 cells. Morphologic changes were observed in LRH1 stable overexpressing Capan-1 and AsPC-1 cells. Compared to vector control, LRH1 stable overexpressing Capan-1 and AsPC-1 cells produced spheres with increased size (**p < 0.01) and (C) Significant reduction in the size of spheres was detected in three MIA PaCa2 cells expressing specific LRH1-shRNAs (**p < 0.05).