Table 2.
Uni- and multivariate analysis of risk factors for post-ERC cholangitis
| Variable | HR (univariate) | p-value | HR (multivariate) | p-value |
|---|---|---|---|---|
| Choledocholithiasis | 3.95 (1.07–14.64) | 0.040 | 2.72 (0.63–10.02) | 0.096 |
| Post OLT | 0.37 (0.15–0.92) | 0.032 | 0.52 (0.21–1.32) | 0.086 |
| Malignant disease | 0.18 (0.038–0.325) | 0.587 | –- | –- |
| Smoking | 0.39 (0.22–0.57) | 0.901 | –- | –- |
| Age | 60.61(54.75–66.47) | 0.778 | –- | –- |
| EPT before inclusion | 0.36 (0.18–0.53) | 0.627 | –- | –- |
| EPT during the study period | 0.66 (0.49–0.83) | 0.131 | –- | –- |
Data are expressed as case numbers (percentage) or mean ± standard deviation, ERC endoscopic retrograde cholangitis, EPT endoscopic papillotomy, OLT orthotopic liver transplantation, CRP c-reactive protein, mg/dl milligrams/decilitre, ALT alanine transferase, AST aspartate aminotransferase, U/l Units/litre, GGT gamma glutamyl transferase, g/l grams/litre, NAFLD non-alcoholic fatty liver disease, PBC primary biliary cholangitis, PSC primary sclerosing cholangitis, AIH autoimmune hepatitis, mg/dl milligrams/decilitre, G/l grams/litre, mmol/l millimole/litre, ml/min/m2 millilitres/minute/square meter, U/l Units/litre, sec second, µg/l microgram/litre