Table 5.
Skeletal malformations of 20 days old rat fetuses following treatment of pregnant rats with 70% ethanol extract of M. stenopetala leaf
| Groups | Percent of skeletal malformations | ||||||
|---|---|---|---|---|---|---|---|
| Hyoida | Sternuma | Rsb | CVd | TVb | LVd | SCVc | |
| G-I: ((n = 27) | 0 | 11.1 | 0 | 0 | 0 | 0 | 7.4 |
| G-II (n = 27) | 0 | 14.8 | 0 | 0 | 0 | 0 | 11.1 |
| G-III (n = 27) | 0 | 22.2 | 0 | 0 | 0 | 0 | 18.5 |
| G-IV (n = 27) | 0 | 11.1 | 0 | 0 | 0 | 0 | 7.4 |
| G-V (n = 27) | 0 | 7.4 | 0 | 0 | 0 | 0 | 7.4 |
Results are expressed as percentage of skeletal malformations (chi-square)
G-I: 250 mg/kg, G-II: 500 mg/kg, G-III: 1000 mg/kg treated groups; G-IV: pair-fed and G-V: ad libitum control groups
CV Cervical vertebrae, TV Thoracic vertebrae, LV Lumbar vertebrae, SCV Sacro-caudal vertebrae
aSternum with less than 4 ossification centers and hyoid bone not showing signs of ossification
bThoracic vertebrae with less than 13 ossification centers and with less than 13 ribs
cCaudal vertebrae with less than 4 ossification centers
dCervical vertebrae with less than 7 ossification centers and Lumbar vertebrae with less than 5 ossification centers