Table 2.

Most used osteosarcoma cell lines

Osteosarcoma cells	Use in research	Refs.
MG-63	Testing of materials for use in bone tissue engineering Cancer treatment research	[2, 71]
Saos-2	Application in bone tissue engineering Research on cancer, metastatic problems, recurrence	[72, 73]
143B	Cell migration and proliferation research Research on useful substances for reducing proliferation and viability	[74–76]
HOS	Research on active substances that cause apoptosis and reduce viability	[77, 78]
U-2 OS	Testing of tomatidine cytotoxicity against cancer	[79–81]
143.98.2	Cytotoxicity testing of doxorubicin and cisplatin in the 2D culture and 3D scaffold	[82]
SJSA-1	Cytotoxic effect of lycorine stopping the cell cycle and causing apoptosis Development of a therapeutic agent targeting canonical Wnt/β-catenin	[81, 83]
MNNG/HOS	Research on oncogenes	[84]