Table 1. Characteristics of study participants.
All variables are reported as n (%) unless otherwise stated.
BMI: body mass index; SCD: sickle cell disease; G6PD: glucose 6 phosphatase dehydrogenase; Hb: hemoglobin; MCV: mean corpuscular volume; LDL: lactate dehydrogenase; AST: aspartate transaminase
| Demographic Variables | n=54 |
| Age, mean (SD) (years) | 11.9 (3.48) |
| BMI, mean (SD) | 17.54 (3.62) |
| Gender | |
| Female | 18 (33.3) |
| Male | 36 (66.7) |
| Age at diagnosis of SCD, mean (SD) (years) (n=51) | 3.49 (2.92) |
| Genotype | |
| HbSS-HbSB0 | 51 (94.4) |
| Others | 3 (5.6) |
| SCD severity | |
| Mild-moderate | 35 (64.83) |
| Severe | 19 (35.2) |
| Comorbidities | |
| Hyperactive airway disease | |
| No | 37 (68.5) |
| Yes | 17 (31.5) |
| G6PD deficiency | |
| No | 49 (90.7) |
| Yes | 5 (9.3) |
| Baseline Hematological Parameters | |
| Hb level, mean (SD) (g/dl) | 8.70 (1.56) |
| HbS %, mean (SD) | 74.15 (8.87) |
| HbF %, mean (SD) | 20.30 (9.03) |
| HbA %, mean (SD) | 1.17 (4.97) |
| HbA2 %, mean (SD) | 3.11 (1.04) |
| MCV, mean (SD) (fl) | 83.97 (11.97) |
| Hemolytic Parameters | |
| LDL, mean (SD) (u/l) (n=51) | 449.75 (197.40) |
| Reticulocyte percentage, mean (SD) | 10.79 (7.51) |
| Bilirubin, mean (SD) (umol/l) (n=52) | 41.34 (46.51) |
| AST, mean (SD) (u/l) (n=52) | 39.38 (12.78) |