Table 3.
Adjusted OR (95% CI, p value) | ||
---|---|---|
Primary outcomes | ||
Any parenchymal hemorrhage on follow up imaging* | First tertile (TC ⩽ 130 mg/dl) | 1.16 (0.99–1.34, p = 0.056) |
Second tertile (TC 130–200 mg/dl) | 1.25 (1.02–1.53, p = 0.034) | |
Third tertile (TC ⩾ 200 mg/dl) | Ref. | |
Moderate or severe CED on follow up imaging § | First tertile | 1.24 (1.10–1.40, p = 0.003) |
Second tertile | 1.29 (1.09–1.52, p = 0.001) | |
Third tertile | Ref. | |
Statins | 0.89 (0.79–1.002, p = 0.054) | |
Secondary outcomes | ||
SICH NINDS* | First tertile (TC ⩽ 130 mg/dl) | 1.18 (1.04–1.33, p = 0.012) |
Second tertile (TC 130–200 mg/dl) | 1.17 (0.98–1.39, p = 0.089) | |
Third tertile (TC ⩾ 200 mg/dl) | Ref. | |
SICH ECASS* | First tertile | 1.31 (1.07–1.6, p = 0.008) |
Second tertile | 1.37 (1.04–1.8, p = 0.023) | |
Third tertile | Ref. | |
SICH SITS-MOST* | First tertile | 1.04 (0.80–1.46, p = 0.771) |
Second tertile | 0.902 (0.60–1.35, p = 0.617) | |
Third tertile | Ref. | |
Any CED § | First tertile | 1.19 (1.03–1.38, p = 0.016) |
Second tertile | 1.25 (1.12–1.39, p < 0.001) | |
Third tertile | Ref. | |
Severe CED on follow up imaging § | First tertile | 1.41 (1.06–1.88, p = 0.018) |
Second tertile | 1.17 (0.94–1.45, p = 0.159) | |
Third tertile | Ref. | |
Secondary late outcomes | ||
mRS 0–2 at 90 days § | First tertile (TC ⩽ 130 mg/dl) | 0.96 (0.87–1.06, p = 0.43) |
Second tertile (TC 130–200 mg/dl) | 1.03 (0.9–1.18, p = 0.68) | |
Third tertile (TC ⩾ 200 mg/dl) | Ref. | |
Statins | 1.11 (1.04–1.19, p = 0.003) | |
Death at 90 days § | First tertile | 0.97 (0.85–1.1, p = 0.64) |
Second tertile | 0.93 (0.78–1.11, p = 0.44) | |
Third tertile | Ref. |
Variables in the models
: age, NIHSS baseline, SBP baseline, glucose baseline, hypertension, diabetes, previous AF, treatment acetylsalicylic acid, treatment statins, IVT and/or EVT, SBP at 24 h.
: age, NIHSS baseline, SBP baseline, glucose baseline, hypertension, diabetes, previous AF, treatment acetylsalicylic acid, treatment statins, IVT and/or EVT, SBP at 24 h, any PH.