Table 1.
Basic Demographic Details of Participants
| Parameters | IP (Mean (SD)) | Placebo (Mean (SD)) | p-value |
|---|---|---|---|
| N | 27 | 32 | – |
| Age (years) | 52.63 (8.23) | 53.72 (6.92) | 0.78 |
| Weight (Kg) | 68.34 (8.14) | 70.14 (10.86) | 0.48 |
| BMI (Kg/m2) | 27.14 (3.23) | 26.80 (3.50) | 0.70 |
| Duration of diabetes (years) | 8.09 (5.70) | 7.95 (6.23) | 0.931 |
| Clinical neurological examination (CNE) score | 12.59 (4.23) | 12.19 (5.41) | 0.37 |
| Neuropathic pain diagnostic questionnaire (dPN4) | 6.93 (1.14) | 6.75 (1.55) | 0.52 |
| PI-NRS (Index Limb) | 7.81 (0.96) | 7.84 (1.08) | 0.92 |
| Pulse rate (bpm) | 79.93 (4.17) | 79.38 (4.78) | 0.75 |
| SBP (mm Hg) | 125.03 (8.60) | 123.66 (7.42) | 0.43 |
| DBP (mm Hg) | 77.14 (4.21) | 78.03 (4.40) | 0.30 |
| HbA1c (%) | 8.37 (0.85) | 8.16 (0.86) | 0.30 |
| AST (U/L) | 24.59 (8.25) | 24.27 (12.63) | 0.23 |
| ALT (U/L) | 27.37 (16.00) | 25.56 (18.17) | 0.35 |
| Serum Creatinine (mg/dL) | 0.79 (0.27) | 0.82 (0.23) | 0.55 |
| Gender Distribution, n (%) | |||
| Male | 13 (48.15%) | 17 (53.13%) | 0.93 |
| Female | 14 (51.85%) | 15 (46.88%) | |
| Medical History, n (%) | |||
| Hyperacidity, n (%) | 1 (3.45%) | 0 (0.00%) | |
| Hypertension, n (%) | 11 (37.93%) | 16 (50.00%) | |
Notes: p-value was calculated using two sample t-test(T)/Mann Whitney-U test(U).
Abbreviations: SD, Standard deviation; n, Number of participants.