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. Author manuscript; available in PMC: 2023 Apr 3.
Published in final edited form as: Bioorg Med Chem Lett. 2016 Nov 25;27(2):254–260. doi: 10.1016/j.bmcl.2016.11.064

Scheme 1.

Scheme 1.

Synthesis of probes. Reagents and conditions: (a) 10% Pd/C, H2, MeOH, 2–6 h; (b) Cbz-Pro-OH, HOBt, EDCl, Et3N, MeCN, 15 h; (c) sulfonated Cy5 carboxylic acid, HCTU or PyBOP, Et3N, 5 h-overnight; (d) 30% N2H4H2O, MeCN/H2O, 15 h.