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Male C57BL/6N mice were randomly assigned to receive normal drinking water (control) or water supplemented with 1% (v/v) 3,3-dimethyl-1-butanol (DMB) beginning in middle age (18 months) and continued into late life (up to 27 months). Mice were studied at 18, 21, 24 and 27 months of age and compared to a reference group of young adult (5 months) mice.
