| Methods |
This is a RCT in which all pregnant women attending the outpatient obstetrics clinic at the Catholic University’s Clinical Hospital (Chile). |
| Participants |
Women with less than 16 weeks of pregnancy were selected (n = 153). |
| Interventions |
Treatment group received a preparation containing equal quantities of iron and folic acid, 350 µg (plus 500 mg of ascorbic acid) (n =78 and 75). |
| Outcomes |
Haemoglobin (g/dL), haematocrit (%), serum iron (µg/dL), transferrin (µg/dL), transferrin saturation (%), serum folate (ng/mL), red cell folate (ng/mL), plasmatic volume (mL) (n = 153). |
| Notes |
|
| Risk of bias |
| Bias |
Authors' judgement |
Support for judgement |
| Random sequence generation (selection bias) |
Unclear risk |
Quote: "Women were divided into 2 groups randomly". |
| Allocation concealment (selection bias) |
Unclear risk |
Insufficient information to permit judgement. |
| Blinding (performance bias and detection bias)
All outcomes |
Unclear risk |
Insufficient information to permit judgement. |
| Incomplete outcome data (attrition bias)
All outcomes |
Unclear risk |
Insufficient information to permit judgement. |
| Selective reporting (reporting bias) |
Unclear risk |
Insufficient information to permit judgement. |
| Other bias |
Unclear risk |
No other bias identified but insufficient information available to fully assess this 'Risk of bias' domain. |
