| Methods |
Double‐blind trial, patients were randomly allocated in 2 groups. Initially 31 patients were recruited in the trial, but during the trial 1 participant from each group was excluded. |
| Participants |
Pregnant women of 20 weeks of gestation who were attending clinic affiliated to University of Basel, Switzerland (n = 29). |
| Interventions |
Group 1: ferrous sulphate 80 mg (n = 15), group 2: ferrous sulphate 80 mg + folic acid 350 µg (n = 14). |
| Outcomes |
Pre‐delivery haemoglobin levels (n = 29). |
| Notes |
Women who were already taking multi‐vitamin containing folic acid prior to commencement of trial were excluded. |
| Risk of bias |
| Bias |
Authors' judgement |
Support for judgement |
| Random sequence generation (selection bias) |
Unclear risk |
Patients were randomised and divided into 2 groups. |
| Allocation concealment (selection bias) |
Unclear risk |
Insufficient information to permit judgement. |
| Blinding (performance bias and detection bias)
All outcomes |
Low risk |
Double‐blinded. |
| Incomplete outcome data (attrition bias)
All outcomes |
Low risk |
Number excluded were not reported while their reasons were described. Attrition (6%) was reported but reasons were not given. |
| Selective reporting (reporting bias) |
Unclear risk |
Insufficient information to permit judgement. |
| Other bias |
Unclear risk |
No other bias identified but insufficient information available to fully assess this 'Risk of bias' domain. |
