| Trial name or title |
High dose folic acid supplementation throughout pregnancy for pre‐eclampsia prevention (FACT) |
| Methods |
Double blind (participant, caregiver, investigator, outcomes assessor) randomised intervention trial with parallel assignment at Ottawa Hospital Research Institute |
| Participants |
Pregnant women at high risk of developing pre‐eclampsia |
| Interventions |
Folic acid 4 mg, folic acid 1.0 mg x 4 tablets will be taken daily by oral administration. The majority of women in the study will routinely take 1.0 mg folic acid in a prenatal vitamin supplement, as recommended by their primary obstetrical provider; the study requirements do not require that participants change their practice. Therefore the actual total daily dose may be up to 5.1 mg of folic acid |
| Outcomes |
Pre‐eclampsia, Preterm birth, Stillbirth, Abortion |
| Starting date |
April 2011 |
| Contact information |
Contact: Mark Walker, MD; Contact: Shi Wu Wen, PhD |
| Notes |
Recruiting |
