Table 1.
Characteristics of participants in the training/validation set.
| Characteristic | All participants (N=20,497) | CAD controls (N=17,828) | CAD cases (n=2,669) |
|---|---|---|---|
| Median age (IQR) — years | 62 (19) | 61 (18) | 72 (16) |
| Sex — no. (%) | |||
| Female | 12,470 (61) | 11,110 (62) | 1,360 (51) |
| Male | 8,027 (39) | 6,718 (38) | 1,309 (49) |
| Ethnicity — no. (%) | |||
| African | 5,480 (27) | 4,755 (27) | 725 (27) |
| European | 5,887 (29) | 5,276 (30) | 611 (23) |
| Hispanic | 7,424 (36) | 6,276 (35) | 1,148 (43) |
| Other | 1,704 (8.3) | 1,519 (8.5) | 185 (6.9) |
| Ever smoked — no. (%) | 3,830 (19) | 3,308 (19) | 522 (20) |
| Median vitals (IQR) | |||
| Weight — lbs | 172 (53) | 170 (55) | 180 (37) |
| Height — inches | 65 (5.1) | 65 (5.0) | 66 (5.3) |
| Systolic blood pressure — mmHg | 128 (17) | 127 (18) | 133 (9.7) |
| Diastolic blood pressure — mmHg | 73 (10) | 74 (11) | 72 (6) |
| Pulse — sec−1 | 77 (12) | 77 (12) | 75 (11) |
| Oxygen saturation — % on room air | 98 (1.0) | 98 (1.5) | 97 (0.72) |
| Respirations — min−1 | 18 (1.0) | 18 (1.1) | 18 (0.52) |
| Temperature — °F | 98 (0.55) | 98 (0.60) | 98 (0.21) |
| Median laboratory measurement (IQR) | |||
| Low-density lipoprotein cholesterol — mg/dL | 100 (35) | 101 (34) | 90 (31) |
| High-density lipoprotein cholesterol — mg/dL | 53 (19) | 54 (19) | 48 (17) |
| Triglycerides — mg/dL | 115 (67) | 114 (67) | 124 (65) |
| Glucose — mg/dL | 92 (22) | 91 (20) | 103 (43) |
| Hemoglobin A1c — % | 5.7 (0.80) | 5.7 (0.73) | 5.1 (1.5) |
| Troponin-I — ng/dL | 0.011 (0.040) | 0.010 (0.035) | 0.023 (0.13) |
| Lactate dehydrogenase — U/L | 213 (44) | 211 (42) | 224 (53) |
| Erythrocyte sedimentation rate — mm/hr | 22 (24) | 21 (23) | 33 (27) |
| Comorbidities — no. (%) | |||
| Hypercholesterolemia | 10,748 (52) | 8,506 (48) | 2,207 (83) |
| Hypertension | 11,762 (57) | 9,376 (53) | 2,365 (89) |
| Type 2 diabetes | 6,395 (31) | 4,834 (27) | 1,529 (57) |
IQR, interquartile range; no., number; ethnicity, self-reported ethnicity; other, other miscellaneous ethnicities besides the ones listed.