Table 2.
Absolute and relative changes of lipid levels after induction therapy.
| Total cholesterol, mmol/L | HDL-c, mmol/L | LDL-c, mmol/L | Triglycerides, mmol/L | Apolipoprotein B, g/L | Lp(a), nmol/L | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Median (IQR) | % | P | Median (IQR) | % | P | Median (IQR) | % | P | Median (IQR) | % | P | Median (IQR) | % | P | Median (IQR) | % | P | |
| CORT (n = 29) | +0.40 (−0.10 to 0.85) | +8 | 0.009 | +0.19 (−0.02 to 0.34) | +15 | 0.002 | +0.19 (−0.19 to 0.50) | +6 | ns | +0.12 (−0.25 to 0.12) | +9 | ns | _0.05 (−0.03 to 0.12) | +6 | ns | −2.0 (−12 to 4) | −4 | ns |
| BUD (n = 20) | +0.30 (-0.25 to 0.48) | +7 | ns | +0.11 (−0.01 to 0.32) | +9 | ns | +0.15 (−0.32 to 0.50) | +6 | ns | +0.09 (−0.29 to 0.20) | +7 | ns | −0.05 (−0.04 to 0.12) | +7 | ns | −1 (−11 to 5) | −1 | ns |
| PRED (n = 9) | +0.90 (0.20 to 1.25) | +26 | 0.024 | +0.30 (-0.07 to 0.66) | +31 | 0.022 | +0.30 (0.04 to 0.50) | +12 | 0.048 | +0.20 (−0.04 to 0.98) | +16 | ns | −0.20 (−0.02 to 0.13) | +3 | ns | −5 (−16 to 1) | −16 | 0.042 |
| THIO (n = 27) | −0.18 (−0.53 to 0.15) | −4 | ns | +0.03 (−0.13 to 0.12) | +2 | ns | −0.12 (−0.35 to 0.18) | −7 | ns | −0.11 (−0.40 to 0.23) | −10 | ns | −0.04 (−0.15 to 0.02) | −3 | ns | −6 (−27 to 0) | −15 | 0.003 |
| MTX (n = 10) | −0.10 (−0.65 to 0.20) | −2 | ns | 0 (−0.19 to 0.05) | 0 | ns | +0.03 (−0.51 to 0.21) | +1 | ns | −0.27 (−0.36 to 0.48) | −2 | ns | −0.02 (−0.13 to 0.01) | −2 | ns | −0.5 (−6 to 2) | −1 | ns |
| IFX (n = 21) | 0 (−0.20 to 0.45) | 0 | ns | +0.01 (−0.1 to 0.15) | +1 | ns | 0 (−0.11 to 0.41) | 0 | ns | 0.00 (−0.28 to 0.41) | 0 | ns | 0.00 (−0.08 to 0.03) | 0 | ns | 0 (−28 to 0.5) | 0 | ns |
| ADA (n = 30) | +0.10 (−0.23 to 0.33) | +3 | ns | +0.03 (−0.08 to 0.18) | +2 | ns | +0.01 (−0.56 to 0.58) | 0 | ns | 0 (−0.20 to 0.22) | 0 | ns | −0.01 (−0.09 to 0.03) | 0 | ns | −2 (−20 to 3) | −10 | ns |
| VEDO (n = 28) | 0 (−0.40 to 0.20) | 0 | ns | −0.07 (−0.23 to 0.09) | −5 | ns | −0.12 (−0.32 to 0.37) | −4 | ns | +0.06 (−0.36 to 0.44) | +5 | ns | −0.04 (−0.10 to 0.04) | −5 | ns | 0 (−6 to 2) | 0 | ns |
| UST (n = 35) | +0.10 (−0.30 to 0.40) | +3 | ns | +0.10 (−0.02 to 0.20) | +7 | ns | +0.07 (−0.15 to 0.18) | +3 | ns | +0.02 (−0.31 to 0.24) | −1 | ns | −0.03 (−0.07 to 0.07) | −4 | ns | 0 (−9 to 8) | 0 | ns |
| TOFA (n = 18) | +0.90 (0.38 to 1.43) | +20 | 0.002 | +0.41 (−0.14 to 0.71) | +25 | 0.028 | +0.73 (0.05 to 1.15) | +26 | 0.002 | -0.09 (−0.55 to 0.51) | −6 | ns | +0.03 (−0.09 to 0.15) | −5 | ns | −0.05 (−4 to 3) | −1 | ns |