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. 2022 Jun 14;29(4):570–578. doi: 10.1093/ibd/izac121

Table 2.

Decrease of SCCAI and its components after start of tofacitinib throughout the 56-day induction period.

SCAAI components Baseline (n = 96) Day 3
(n = 92)
Day 7
(n = 94)
Day 14
(n = 90)
Day 28
(n = 88)
Day 56
(n = 79)
SCCAI score 5.63 4.55 3.78 3.32 3.40 3.18
<0.0001a <0.0001a <0.0001a <0.0001a <0.0001a
Frequency day 1.18 0.93 0.86 0.66 0.60 0.61
<0.0029a <0.0006a <0.0001a <0.0001a <0.0001a
Rectal bleeding 1.20 0.91 0.70 0.63 0.68 0.73
<0.0002a <0.0001a <0.0001a <0.0001a <0.0001a
Urgency 1.36 1.21 0.95 0.89 0.91 0.81
<0.0013a <0.0001a <0.0001a <0.0001a <0.0001a

aSignificance level compared to baseline.