Table 2.
Patients’ characteristics stratified according to biologic therapy at baseline.
| N | Total N = 141 |
SD | N | Biologic Therapy at Baseline N = 42 (29.8%) |
SD | N | No Biologic Therapy at Baseline N = 99 (70.2%) |
SD | P a | |
|---|---|---|---|---|---|---|---|---|---|---|
| %/mean | %/mean | %/mean | ||||||||
| Age | 141 | 45.1 | 14.2 | 42 | 44.0 | 13.7 | 99 | 45.6 | 14.5 | 0.5120 |
| Age at diagnosis | 141 | 33.9 | 12.8 | 42 | 31.7 | 12.8 | 99 | 34.9 | 12.5 | 0.1698 |
| Gender | 0.2847 | |||||||||
| Male | 81 | 57.4 | 27 | 64.3 | 54 | 54.5 | ||||
| Female | 60 | 42.6 | 15 | 35.7 | 45 | 45.5 | ||||
| Smoking Status | 0.0852 | |||||||||
| Non smoker | 52 | 36.9 | 20 | 47.6 | 32 | 32.3 | ||||
| Ex smoker | 61 | 43.2 | 12 | 28.6 | 49 | 49.5 | ||||
| Smoker | 28 | 19.9 | 10 | 23.8 | 18 | 18.2 | ||||
| Montreal Classification | ||||||||||
| Age | 0.1788 | |||||||||
| A1 < 16 | 8 | 36.9 | 3 | 7.2 | 5 | 5.0 | ||||
| A2 (17-40) | 87 | 43.3 | 30 | 71.4 | 57 | 57.6 | ||||
| A3 (>40) | 28 | 19.9 | 9 | 21.4 | 37 | 37.4 | ||||
| Location | 0.5418 | |||||||||
| L1: ileal | 88 | 62.4 | 25 | 59.5 | 63 | 63.6 | ||||
| L2: colonic | 3 | 2.1 | 0 | 0.0 | 3 | 3.0 | ||||
| L3: ileocolonic | 50 | 35.5 | 17 | 40.5 | 33 | 33.3 | ||||
| L4: isolated upper | 0 | 0.0 | 0 | 0.0 | 0 | 0.0 | ||||
| GI | ||||||||||
| Behavior | 0.5331 | |||||||||
| B1: nonstricturing, | 19 | 13.5 | 7 | 16.7 | 12 | 12.1 | ||||
| nonpenetrating | ||||||||||
| B2: stricturing | 77 | 54.6 | 20 | 47.6 | 57 | 57.6 | ||||
| B3: penetrating | 45 | 31.9 | 15 | 35.7 | 30 | 30.3 | ||||
| Preoperative History | ||||||||||
| Topical steroids | 45 | 31.9 | 13 | 31.0 | 32 | 32.3 | 0.8731 | |||
| Systemic steroids | 66 | 46.8 | 24 | 57.1 | 42 | 42.4 | 0.1092 | |||
| Thiopurine | 38 | 27.0 | 16 | 38.1 | 22 | 22.2 | 0.0521 | |||
| Methotrexate | 6 | 4.3 | 3 | 7.1 | 3 | 3.0 | 0.2685 | |||
| Familiarity for IBD | 0.5474 | |||||||||
| Positive | 17 | 12.1 | 4 | 9.5 | 13 | 13.1 | ||||
| Negative | 124 | 87.9 | 38 | 90.5 | 86 | 86.9 | ||||
| Perianal Disease | 0.0008 | |||||||||
| Present | 24 | 17.0 | 14 | 33.3 | 10 | 10.1 | ||||
| Absent | 117 | 83.0 | 28 | 66.7 | 89 | 89.9 | ||||
| Upper GI | 0.6261 | |||||||||
| Present | 5 | 3.5 | 1 | 2.4 | 4 | 4.0 | ||||
| Absent | 136 | 96.5 | 41 | 97.6 | 95 | 96.0 | ||||
| Concomitant Rheumatologic disease | 0.0829 | |||||||||
| Present | 10 | 7.1 | 5 | 11.9 | 5 | 94.9 | ||||
| Absent | 131 | 92.9 | 31 | 88.1 | 94 | 5.1 |
Abbreviations: SD, standard deviation, IBD, inflammatory bowel disease, GI, gastrointestinal,.
aThe χ2 test for qualitative variables and Student t test for quantitative variables.