Table 2.
Circulating concentrations of glucose, insulin and cholesterols in women with GDM in DHA supplementation vs. control groups.
| DHA (n = 30) | Control (n = 38) | p * | |
|---|---|---|---|
| First prenatal visit | |||
| Gestational age (weeks) | 14.3 ± 4.1 | 13.2 ± 1.9 | 0.16 |
| Fasting blood glucose (mmol/L) | 5.2 ± 0.7 | 5.0 ± 0.4 | 0.26 |
| Fasting insulin (pmol/L) | 49.1 (33.7–79.9) | 51.7 (30.8–70.4) | 0.44† |
| Total triglyceride (mmol/L) | 2.1 ± 0.8 | 1.7 ± 0.6 | 0.047 |
| Total cholesterol (mmol/L) | 4.8 ± 0.8 | 4.6 ± 0.9 | 0.34 |
| HDL cholesterol (mmol/L) | 1.8 ± 0.4 | 1.9 ± 0.5 | 0.84 |
| LDL cholesterol (mmol/L) | 2.4 ± 0.6 | 2.2 ± 0.6 | 0.44 |
| Creatinine (umol/L) | 42.0 ± 5.1 | 42.9 ± 6.4 | 0.56 |
| 75 g OGTT at 24–28 weeks of gestation | |||
| Fasting blood glucose (mmol/L) | 5.2 ± 0.6 | 5.0 ± 0.4 | 0.26 |
| 1-h blood glucose (mmol/L) | 9.6 ± 1.3 | 9.6 ± 1.7 | 0.87 |
| 2-h blood glucose (mmol/L) | 7.6 ± 1.7 | 7.3 ± 1.7 | 0.57 |
| Fasting insulin (pmol/L) | 66.6 (43.2–80.9) | 58.8 (34.5–88.3) | 0.73† |
| 2-h insulin (pmol/L) | 356.3 (190.2–504.8) | 339.6 (275.6–513.3) | 0.78† |
| HbA1c (%) | 5.4 ± 0.7 | 5.2 ± 0.4 | 0.11 |
| Last visit in late gestation | |||
| Gestational age (weeks) | 36.0 ± 7.3 | 33.7 ± 4.6 | 0.16 |
| Fasting blood glucose (mmol/L) | 4.8 ± 0.6 | 4.8 ± 0.6 | 0.94 |
| HbA1c (%) | 5.9 ± 1.2 | 5.5 ± 0.5 | 0.18 |
| Total triglyceride (mmol/L) | 3.3 ± 1.3 | 3.3 ± 1.0 | 0.99 |
| Total cholesterol (mmol/L) | 5.9 ± 1.1 | 5.9 ± 1.0 | 0.96 |
| Creatinine (μmol/L) | 45.7 ± 7.4 | 44.4 ± 6.4 | 0.48 |
*
p Values in t-tests for comparisons between the two groups.
†
p Values for comparisons between the two groups in log-transformed data for insulin.
Data represented are mean ± SD or median (IQR).
DHA, docosahexaenoic acid; GDM, gestational diabetes mellitus; HbA1c, glycated hemoglobin; HDL, high-density lipoprotein; LDL, low-density lipoprotein.
p Values in bold: p < 0.05.