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. 2023 Mar 30;7(4):e0111. doi: 10.1097/HC9.0000000000000111

FIGURE 1.

FIGURE 1

Representative images of in situ hybridization staining of liver sections. (A) Representative images of sections from immune-tolerant (IT) patients. The majority of the hepatocytes are positive. (B) Representative images of sections from HBeAg-positive immune-active (HBeAg+IA) patients. A proportion of hepatocytes are positive for both HBV RNA and DNA. (C) Representative images of sections from inactive chronic hepatitis B (IC) patients. Only a few hepatocytes are positive for HBV RNA and DNA, and most signals are only seen in the nucleus. (D) Representative images of sections from HBeAg-negative immune-active (HBeAg−IA) patients. A small proportion of hepatocytes are positive for HBV RNA and DNA (×400). (E) The percentage of HBV RNA-positive hepatocytes in hepatitis B patients. (F) The percentage of HBV DNA-positive hepatocytes in hepatitis B patients. Abbreviation: NS, nonsignificant.