Table III.
Progesterone (N = 136) | Placebo (N = 133) | |||||
---|---|---|---|---|---|---|
n/N (%) | n/N (%) | RR | 95% CI | P | P for interaction | |
No. of miscarriages | ||||||
0 | 58/69 (84.1) | 47/56 (83.9) | 1 | 0.86–1.17 | 0.984 | |
≥1 | 54/67 (80.6) | 65/77 (84.4) | 0.95 | 0.82–1.11 | 0.55 | 0.664 |
Infertility for current pregnancy | ||||||
No | 90/106 (84.9) | 88/104 (84.6) | 1 | 0.89–1.13 | 0.953 | |
Yes | 19/25 (76.0) | 19/23 (82.6) | 0.92 | 0.69–1.23 | 0.572 | 0.585 |
Maternal age | ||||||
<40 years | 107/131 (81.7) | 108/127 (85.0) | 0.96 | 0.86–1.07 | 0.469 | |
≥40 years | 5/5 (100.0) | 4/6 (66.7) | 1.5 | 0.83–2.72 | 0.181 | 0.13 |
Baseline progesterone level | ||||||
<25 nmol/l | 2/10 (20.0) | 1/5 (20.0) | 1 | 0.11–9.23 | 1 | |
25–50 nmol/l | 40/49 (81.6) | 40/50 (80.0) | 1.02 | 0.84–1.24 | 0.837 | 0.985 |
>50 nmol/l | 68/74 (91.9) | 66/73 (90.4) | 1.02 | 0.92–1.12 | 0.753 | 0.988 |
Gestation at recruitment | ||||||
<8 weeks | 70/89 (78.7) | 66/82 (80.5) | 0.98 | 0.84–1.14 | 0.767 | |
8–10 weeks | 42/47 (89.4) | 46/51 (90.2) | 0.99 | 0.87–1.13 | 0.892 | 0.894 |