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. 2023 Feb 20;38(4):560–568. doi: 10.1093/humrep/dead029

Table III.

Subgroup analysis of live birth rate.

Progesterone (N = 136) Placebo (N = 133)
n/N (%) n/N (%) RR 95% CI P P for interaction
No. of miscarriages
0 58/69 (84.1) 47/56 (83.9) 1 0.86–1.17 0.984
≥1 54/67 (80.6) 65/77 (84.4) 0.95 0.82–1.11 0.55 0.664
Infertility for current pregnancy
No 90/106 (84.9) 88/104 (84.6) 1 0.89–1.13 0.953
Yes 19/25 (76.0) 19/23 (82.6) 0.92 0.69–1.23 0.572 0.585
Maternal age
<40 years 107/131 (81.7) 108/127 (85.0) 0.96 0.86–1.07 0.469
≥40 years 5/5 (100.0) 4/6 (66.7) 1.5 0.83–2.72 0.181 0.13
Baseline progesterone level
<25 nmol/l 2/10 (20.0) 1/5 (20.0) 1 0.11–9.23 1
25–50 nmol/l 40/49 (81.6) 40/50 (80.0) 1.02 0.84–1.24 0.837 0.985
>50 nmol/l 68/74 (91.9) 66/73 (90.4) 1.02 0.92–1.12 0.753 0.988
Gestation at recruitment
<8 weeks 70/89 (78.7) 66/82 (80.5) 0.98 0.84–1.14 0.767
8–10 weeks 42/47 (89.4) 46/51 (90.2) 0.99 0.87–1.13 0.892 0.894