ERS/ESICM/ESCMID/ALAT guidelines for the management of severe community-acquired pneumonia

. 2023 Apr 4:1–18. Online ahead of print. doi: 10.1007/s00134-023-07033-8

Recommendation
We suggest the addition of macrolides, not fluoroquinolones, to beta-lactams as empirical antibiotic therapy in hospitalised patients with sCAP. Conditional recommendation, very low quality of evidence.
Remark: The task force also considered the duration of treatment of macrolides being between 3 and 5 days. This would be a reasonable timing especially in the context of de-escalation therapy.

Recommendation

We suggest the addition of macrolides, not fluoroquinolones, to beta-lactams as empirical antibiotic therapy in hospitalised patients with sCAP.

Conditional recommendation, very low quality of evidence.

Remark: The task force also considered the duration of treatment of macrolides being between 3 and 5 days. This would be a reasonable timing especially in the context of de-escalation therapy.