Figure 2.

NLRP3 inhibition decreased maternal MAP and fetal reabsorption rates in placenta ischemic rats. A: maternal MAP as measured by direct carotid catheterization. B: placenta weight, values expressed as average placenta weight in each litter. C: fetal weight, values expressed as average pup weight in each litter. D: fetal reabsorption rate, calculated as number of reabsorbed fetuses divided by total litter size. Data were presented as means ± SD. *P < 0.05 vs. NP + Vehicle, #P < 0.05 vs. RUPP + Vehicle, n = 7–10. MAP, mean arterial pressure; NP, normal pregnant; RUPP, reduced uterine perfusion pressure.