Figure 5.
cNK activation in the circulation, placenta, and kidney were reduced after NLRP3 inhibition. NLRP3 inhibition also reduced circulating and placental TH17 populations. cNK cell populations were measured via flow cytometry in circulation (A), placenta (B), and kidney (C). TH17 cell populations were measured via flow cytometry in circulation (D), placenta (E), and kidney (F). Data were presented as mean ± SD. *P < 0.05 vs. NP + Vehicle, #P < 0.05 vs. RUPP + Vehicle, n = 4–8. NP, normal pregnant; RUPP, reduced uterine perfusion pressure.