Skip to main content
. 2023 Mar 22;8(6):e162436. doi: 10.1172/jci.insight.162436

Figure 6. Inhibiting METTL16 expression in MSCs strengthens their monocyte recruitment capacity in vivo.

Figure 6

(A) Schematic representation of the in vivo monocyte migration assay. (B) Representative flow cytometry histograms of CFSE-labeled monocytes in peritoneal lavage fluids of NOD/SCID mice. (C) Representative flow cytometry histograms of CFSE-labeled monocytes in the spleens of NOD/SCID mice. (D) Flow cytometry analysis of the percentage of CFSE-positive monocytes in peritoneal lavage fluids (n = 9). (E) Flow cytometry analysis of the percentage of CFSE-positive monocytes in the spleen (n = 9). (F) Relative CFSE-positive monocytes in peritoneal lavage fluids normalized to CFSE-positive cells in spleen (n = 9). Data are presented as the mean ± SD. One-way ANOVA followed by Bonferroni’s test was performed in D–F. *P < 0.05; ***P <0.001; ****P < 0.0001. NS, not significant; MSCs, mesenchymal stem cells.