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. 2022 Nov 24;30(4):885–896. doi: 10.1038/s41418-022-01084-y

Fig. 6. Caspase-8 restrains autophagy after HSV-1 infection in U937 cells.

Fig. 6

A Anti-LC3 western blot analyses of wt and caspase-8−/− U937 cells either mock-infected (0 h) or infected with HSV-1 for 8 and 16 h. β-Actin served as a loading control. B Quantitation of the respective LC3-II protein bands shown in A. Autophagy is significantly increased in caspase-8−/− U937 as compared to wt cells. Data are depicted as relative densities and represent the means of 3 independent experiments ± SD. Statistical evaluation by one-way ANOVA: ***p < 0.001.