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. 2023 Apr 3;9:30. doi: 10.1038/s41526-023-00273-4

Fig. 4. Strength of alterations in clock- and muscle- related genes correlates with the duration of spaceflight/bedrest in mammalian skeletal muscle.

Fig. 4

To explore the differences in differential gene expression based on the duration of spaceflight or bedrest, we grouped the datasets accordingly. The groups for spaceflight datasets were 11 days (GSE10533), 30 days (GSE80223, GSE94381), 33 days (GSE156321), and 37 days (/GLDS-99/-101/-103/-104/-105). The groups for bedrest datasets were 9 days (GLDS-370), 21 days (GSE104999), 60 days (GSE14798), and 90 days (GSE148152). Lollipop plots represent the distribution of differentially expressed clock-regulated genes (NCRGs) and muscle related genes due to spaceflight (a–b) and bedrest (c–d), respectively.