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. 2023 Mar 21;13:1079808. doi: 10.3389/fonc.2023.1079808

Table 2.

Impact of clinical patients and disease characteristics on PET Choline results.

PET-positive (n=161)
N or median % or IQR
PET-positive + SBRT (n=73)
N or median % or IQR
p-value
Age at diagnosis 66 (62-69) 66 (62-70) 0,153
PSA at diagnosis 10 (6.7-17.7) 9,8 (7-19) 0,920
Gleason at diagnosis
≤6 (low risk) 13 8,1% 4 5,5%
4+3 (intermediate risk, favourable) 26 16,1% 13 17,8%
3+4 (intermediate risk, unfavourable) 52 32,3% 19 26,0%
≥8 (high risk) 70 43,5% 37 50,7% 0,133
Hormone therapy (initial)
no 131 81,4% 58 79,5%
yes 30 18,6% 15 20,5% 0,210
PSA post-surgery 0,6 (0.0-0.71) 0,02 (0.0-0.5) 0,123
Adjuvant radiotherapy
no 133 82,6% 44 60,3%
yes 28 17,4% 29 39,7% 0,001*
PSA at recurrence 1,69 (1.00-3.81) 1,22 (0.69-2.43) <0.001*
Recurrence (% yes)
lumbar nodes 6 3,8% 4 5,5% 0,015*
pelvic nodes 43 26,9% 46 63,0% <0.001*
bone 33 20,6% 16 21,9% <0.001*
lung 1 0,6% 0 0,0% 0,461
prostate 97 60,6% 13 17,8% <0.001*
N positive sites at PET
0 0 0,0% 0 0,0%
1-3 150 93,2% 73 100,0%
>3 11 6,8% 0 0,0% <0.001*
Hormone therapy (at recurrence)
no 68 42,8% 38 52,8%
yes 91 57,2% 34 47,2% 0,309
Chemotherapy (at recurrence)
no 148 93,1% 71 98,6%
yes 11 6,9% 1 1,4% 0,120

(*) significant results.