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. 2023 Mar 21;14:1155009. doi: 10.3389/fendo.2023.1155009

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Copyright © 2023 Nie, Yao, Xu, Liu, Yin, Lai, Li, Zhou and Yang

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Correlation analysis of the riskscore expression of m6A in ESCC patients with the sensitivity scores of drugs in the GDSC database. (A) Box plots of specific expression associations between treatment sensitivity and riskscore groupings for multiple oncology therapies. Chemotherapeutic agents include AZD8186_1918, SK269962A_1192, Acetalax_1804, Bl-2536_1086, JQ1_2172, PF-4708671_1129; (B) Correlation heat map analysis further clarifies the therapeutic sensitivity of multiple chemotherapeutic agents with specific each gene in the m6A risk model for expression correlation. * means <0.05, ** means <0.01, *** means <0.001.