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. 2023 Mar 21;14:1145114. doi: 10.3389/fmicb.2023.1145114

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Copyright © 2023 Li, Zhang, Li and Zheng.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Proliferation and CTL activity of lymphocytes in immunized BALB/c mice. (A) The proliferative responses of splenocytes in immunized BALB/c mice. SI, stimulation index. (B) CTL activity of spleen lymphocytes in TG290 mRNA-LNP immunized mice. The horizontal axis indicates the effector-to-target cell ratios. The vertical axis shows the percentage of T. gondii-specific lysis. Data were obtained from triplicate independent experiments and are presented as means ± SD (n = 5). ****p < 0.0001, analyzed by One-way ANOVA with multiple comparisons (compare the mean of each group with the mean of every other group).