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. 2023 Mar 21;14:1145114. doi: 10.3389/fmicb.2023.1145114

Table 2.

Predicted IC50 values from IEDBa for TG290 and SAG1 binding to MHC class II molecules.

MHC II albleleb Start-stopc Percentile rankd
SAG1 TG290 SAG1 TG290
H2-IAb 26–40 28–42 0.95 3.6
H2-IAd 170–184 48–62 2.45 0.49
H2-IEd 14–28 18–32 3.35 0.51
HLA-DRB 1*01:01 12–26 16–30 1.8 2.1
a

The immune epitope database (http://tools.immuneepitope.org/mhcii).

b

H2-IAb, H2-IAd, and H2-IEd alleles are mouse MHC class II molecules; the HLA-DRB1*01:01 allele is a human MHC class II molecule.

c

15 amino acids were chosen for analysis.

d

Low percentile indicates high level binding according to the software instructions.