TABLE 1.
Characteristics | All participants | Autopsy confirmed Alzheimer’s disease |
Autopsy confirmed Lewy body disease |
Autopsy confirmed AD+LBD |
Neither AD nor LBD confirmed at autopsy |
Total number of included participants | 1920 | 788 | 140 | 572 | 420 |
Sex | |||||
Male | 1071 (56%) | 403 (51%) | 92 (66%) | 326 (57%) | 250 (60%) |
Female | 849 (44%) | 385 (49%) | 48 (34%) | 246 (43%) | 170 (40%) |
Race | |||||
White | 1796 (94%) | 734 (93%) | 135 (96%) | 537 (94%) | 390 (93%) |
Black or African American | 58 (3.0%) | 25 (3.17%) | 0 (0.00%) | 18 (3.15%) | 15 (3.57%) |
American Indian or Alaska Native | 2 (0.10%) | 2 (0.25%) | 0 (0.00%) | 0 (0.00%) | 0 (0.00%) |
Native Hawaiian or Pacific Islander | 1 (0.05%) | 0 (0.00%) | 0 (0.00%) | 0 (0.00%) | 1 (0.24%) |
Asian | 14 (0.73%) | 4 (0.51%) | 0 (0.00%) | 5 (0.87%) | 5 (1.19%) |
Multiracial | 36 (1.88%) | 17 (2.16%) | 5 (4%) | 9 (1.57%) | 5 (1.19%) |
Unknown or ambiguous | 13 (0.68%) | 6 (0.76%) | 0 (0.00%) | 3 (0.52%) | 4 (0.95%) |
# of participants at each CDR stage | |||||
CDR 0.5 | 1262 | 524 | 108 | 326 | 304 |
CDR 1.0 | 1368 | 589 | 82 | 461 | 236 |
CDR 2.0 | 831 | 373 | 37 | 298 | 123 |
CDR 3.0 | 609 | 266 | 26 | 212 | 105 |
# of participants at each age stage | |||||
<60 | 196 | 68 | 8 | 57 | 63 |
60–70 | 485 | 173 | 34 | 142 | 136 |
70–80 | 742 | 309 | 53 | 277 | 103 |
80–90 | 738 | 351 | 53 | 221 | 113 |
>=90 | 236 | 118 | 13 | 42 | 63 |
# of participants at each education level (in education years) | |||||
<=12 | 377 (19.64%) | 162 (20.56%) | 30 (21.43%) | 102 (17.83%) | 83 (19.76%) |
12–16 | 852 (44.38%) | 365 (46.32%) | 55 (39.29%) | 253 (44.23%) | 179 (42.62%) |
>16 | 674 (35.10%) | 257 (32.61%) | 55 (39.29%) | 213 (37.24%) | 149 (35.48%) |
Unknown | 17 (0.89%) | 4 (0.51%) | 0 (0.00%) | 4 (0.70%) | 9 (2.14%) |
Mean [STD] age at initial visits | 73.62 [10.53] | 75.16 [9.94] | 74.49 [9.24] | 72.83 [9.54] | 71.53 [12.63] |
Mean [STD] CDR at initial visits | 0.59 [0.35] | 0.59 [0.35] | 0.52 [0.34] | 0.66 [0.34] | 0.51 [0.37] |
Mean [STD] education years | 15.67 [3.03] | 15.56 [3.02] | 15.64 [3.27] | 15.88 [3.04] | 15.59 [2.96] |
The number in the parenthesis is the ratio between the number of participants with that characteristic and the number of all participants or participants with autopsy-confirmed AD or/and LBD results. The number in the bracket is the standard deviation (STD) for participants of that characteristic. Each participant can contribute different data points to different visits with different ages, so the sum of the numbers of participants at each age stage might be larger than the total number of included participants (row 1) of each column. Same case for the number of participants at each CDR stage.