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. Author manuscript; available in PMC: 2023 Apr 4.
Published in final edited form as: J Neurol Sci. 2007 Nov 19;267(1-2):137–141. doi: 10.1016/j.jns.2007.10.019

Fig. 2.

Fig. 2.

A) Southern blot analysis of total DNA obtained from the last muscle biopsy (age 12) of the patient (P) and two age-matched control muscle samples (C1 and C2), showed severe depletion of mtDNA. Probes for mtDNA and the nuclear DNA (nDNA) encoded 18 S rRNA genes have been used. B) Western blot analysis showed normal protein levels of COX II at age 12. Ratios of the mtDNA-encoded COX II relative to the nDNA-encoded ATPase V are indicated.