Table 2.

Cerebral volume differences pre- and post-radiotherapy of glioma

	Pre-RT (mean ± SD)	Post-RT (mean ± SD)	Difference, Δ	p-value
Hippocampus	3.34 ± 1.35	3.2 ± 1.23	-0.14 ± 0.12	< 0.001~
Right Temporal Lobe	56.71 ± 20.8	54.5 ± 19.7	-2.21 ± 1.1	0.006*
Left Temporal Lobe	59.07 ± 19.96	56.11 ± 19.03	-2.96 ± 0.93	< 0.001~
Cerebellum	22.23 ± 10.4	21.33 ± 9.75	-0.9 ± 0.65	< 0.001~
Corpus callosum	3.08 ± 1.26	2.95 ± 1.13	-0.13 ± 0.13	< 0.001~
Amygdala	1.69 ± 0.56	1.61 ± 0.53	-0.08 ± 0.03	< 0.001*
Caudate nucleus	2.12 ± 1.06	2.03 ± 0.99	-0.09 ± 0.07	< 0.001~
Thalamus	5.87 ± 1.5	5.61 ± 1.37	-0.26 ± 0.13	< 0.001~
Spinal cord	13.1 ± 8.22	12.84 ± 8.06	-0.26 ± 0.16	< 0.001*
Brain stem	26.66 ± 5.04	25.86 ± 4.89	-0.8 ± 0.15	< 0.001*
Optic chiasm	0.45 ± 0.32	0.43 ± 0.31	-0.02 ± 0.01	< 0.001~

*Paired t-test

~Wilcoxon-signed rank