Table 4.
Univariate and multivariate linear regression analysis for effect of EAT volume on QFRmin.
| Variable | Univariate analysis | Multivariate analysis | ||
|---|---|---|---|---|
| β coefficient (95% CI) | P-value | β coefficient (95% CI) | P-value | |
| Age | −0.02 (−0.005, 0.001) | 0.241 | ||
| Male | −0.097 (−0.162, −0.033) | 0 . 003 | −0.084 (−0.178, 0.010) | 0.080 |
| BMI | −0.007 (−0.018, 0.003) | 0.189 | ||
| Body surface area | −0.246 (−0.435, −0.057) | 0 . 011 | 0.248 (−0.019, 0.515) | 0.068 |
| Active smoking | −0.136 (−0.208, −0.064) | <0 . 001 | −0.071 (−0.151, 0.008) | 0.078 |
| Hypertension | −0.057 (−0.131, 0.016) | 0.126 | ||
| Diabetes mellitus | −0.067 (−0.137, 0.003) | 0.059 | −0.016 (−0.085, 0.053) | 0.653 |
| Dyslipidemia | −0.099 (−0.165, −0.033) | 0 . 003 | ||
| TC | −0.018 (−0.048, 0.012) | 0.246 | ||
| Triglycerides | −0.021 (−0.041, 0) | 0 . 046 | 0 (−0.020, 0.021) | 0.966 |
| HDL | 0.213 (0.103, 0.322) | <0 . 001 | 0.190 (0.069, 0.311) | 0 . 002 |
| LDL | −0.037 (−0.074, −0.001) | 0 . 046 | −0.051 (−0.088, −0.014) | 0 . 007 |
| Creatinine | −0.002 (−0.005, 0) | 0 . 048 | 0.001 (−0.002, 0.003) | 0.676 |
| Uric acid | 0 (−0.001, 0) | 0.094 | 0 (0, 0.001) | 0.446 |
| FBG | −0.006 (−0.022, 0.009) | 0.412 | ||
| HbA1c | −0.018 (−0.044, 0.009) | 0.193 | ||
| EF | 0.006 (0, 0.012) | 0 . 034 | 0.004 (−0.001, 0.010) | 0.127 |
| CACs (per 100) | −0.014 (−0.020, −0.007) | <0 . 001 | −0.011 (−0.018, −0.005) | 0 . 001 |
| EAT volume (per SD) | −0.073 (−0.105, −0.041) | <0 . 001 | −0.066 (−0.102, −0.030) | <0 . 001 |
BMI, body mass index; CACs, coronary artery calcium score; CI, confidence interval; EAT, epicardial adipose tissue; EF, ejection fraction; FBG, fasting blood glucose; HbA1c, glycated hemoglobin; HDL, high-density lipoprotein; LDL, low-density lipoprotein; QFR, quantitative flow ratio; SD, standard deviation; TC, total cholesterol.
Bold value is statistically significant.