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Results from cytotoxicity assays of combretastatin D-3 (3) and D-4 (4) against cancer cell lines [18].
| Compound | IC50 μg·mL−1 (molar concentration)a | |||
|
| ||||
| KB | BC-1 | NCI-H187 | Vero cells | |
|
| ||||
| 3 | >20 (>60 μM) |
>20 (>60 μM) |
13.0 ± 0.2 (40 μM) |
>50 (>150 μM) |
| 4 | >20 (>65 μM) |
>20 (>65 μM) |
>20 (>65 μM) |
>50 (>160 μM) |
| ellipticine | 0.2–0.3 (≈0.8 μM) | |||
aApproximated values of molar concentration after conversion.
