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. 2023 Mar 29;19:399–427. doi: 10.3762/bjoc.19.31

Table 3.

Solubility comparison of combretastatin D-2 (2) and prodrugs in water at 25 °C [55].

Compound Solubility (mg·mL−1)

2 0.5
184 >70
185 >50
186 20
187 5