Table 1. Number of data sets for which the substructure was determined and the majority of the model was built by the two tested pipelines: starting from E calculated as Friedel pair differences and by multivariate Afro .

The first number in each cell denotes the number of successes using the default substructure-determination protocol and the second number that using the ‘thorough’ substructure-determination protocol with a substantially larger number of trials and a larger number of high-resolution cutoffs.

	No. of data sets (default/thorough)
	Delta	Multivariate
Substructures determined	162/163	168/170
Models built	156/157	161/162