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. Author manuscript; available in PMC: 2023 Apr 4.
Published in final edited form as: Am J Med. 2021 May 1;134(9):1068–1070. doi: 10.1016/j.amjmed.2021.03.038

Table:

Unresolved questions in regards to polypharmacy in heart failure with reduced ejection fraction

Open Questions in Regards to Polypharmacy
Optimal sequencing of medications
Optimal matching of medications to patient profile
In-hospital guideline-directed medical therapy implementation
Efficacy of polypill
Educating and engaging patients and their families in heart failure treatment