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. 2023 Apr 3;18:19. doi: 10.1186/s13011-023-00528-z

Table 2.

Side effects from AAS use

Whole sample (n = 90) Treatment group (n = 41) Non-treatment group (n = 49)
Self-reported AAS-related psychological side effects n % n % n % χ2 p-value
Fatigue 43 47.8 26 63.4 17 34.7 7.38 0.007*
Sleep disorder 59 33.3 30 73.2 29 50.8 1.934 0.164
Depression 33 36.7 20 48.8 13 26.5 4.759 0.029*
Mood swings 61 67.8 29 70.7 32 65.3 0.301 0.583
Anxiety 29 32.2 18 43.9 11 22.4 4.704 0.030*
Paranoia 13 14.4 9 22.0 4 8.2 3.434 0.077
Irritability 54 60.0 23 56.1 31 63.3 0.478 0.489
Short fuse 55 61.1 25 61.0 30 61.2 0.001 0.981
Aggression 38 42.2 18 43.9 20 40.8 0.087 0.768
Jealousy 60 66.7 24 58.5 36 73.5 2.234 0.134
Increased impulsivity 38 42.2 15 36.6 23 46.9 0.981 0.322
Reduced empathy 34 37.8 15 36.6 19 38.8 0.046 0.831
Reduced memory 58 64.4 24 58.5 34 69.4 1.147 0.284
Reduced concentration 32 35.6 18 43.9 14 28.6 2.29 0.130
Self-reported AAS-related physical side effects n % n % n % χ2 p-value
Stretch marks 46 51.1 23 56.1 23 46.9 0.749 0.387
Acne 59 63.3 27 65.9 32 65.3 0.003 0.957
Excessive sweating 61 67.8 33 80.5 28 57.1 5.57 0.018*
Oedema 63 70.0 29 70.7 34 69.4 0.019 0.890
Hair growth 46 51.1 25 61.0 21 42.9 2.933 0.087
Hair loss 29 32.2 10 24.4 19 38.8 2.115 0.146
Ruptured muscles or tendons 24 26.6 12 29.3 12 24.5 0.261 0.610
Injection site pain 72 80.0 34 82.9 38 77.6 0.403 0.525
Abscess 23 25.6 12 29.3 11 22.4 0.546 0.460
Gynecomastia 32 35.6 20 48.8 12 24.5 5.748 0.017*
Reduced libido 30 33.3 16 39.0 14 28.6 1.098 0.295
Sexual dysfunction 25 27.8 14 34.1 11 22.4 1.523 0.217
Testicular atrophy 63 70.0 31 75.6 32 65.3 1.129 0.288

Data are presented as numbers (n) and percentages (%). *Significant difference between the groups (p ≤ 0.05). Fischer’s exact test was used when the expected number were based upon less than five cases.