TABLE 2.
Patient-Level Overall Proportion of Patients With Correct Rate of Detection of Recurrent PCa According to Standard of Truth and Positive Predictive Value (ITT Population) (n = 190)
| Parameter | 18F-PSMA-1007* | 18F-fluorocholine* | P |
|---|---|---|---|
| Undetermined lesions considered positive for PCa recurrence in analysis | |||
| Proportion | 0.82 (0.78–0.86) | 0.65 (0.60–0.71) | |
| Difference in proportion | 0.16 (0.11–0.22) | <0.0001 | |
| Odds ratio | 2.40 (1.79–3.21) | <0.0001 | |
| Positive predictive value | 0.96 (0.93–0.99) | 0.96 (0.93–0.99) | |
| Difference in positive predictive value | 0.002 (0.031–0.035) | 0.90 | |
| Odds ratio | 0.95 (0.42–2.15) | 0.90 | |
| Undetermined lesions considered negative for PCa recurrence in analysis | |||
| Proportion | 0.77 (0.72–0.82) | 0.57 (0.51–0.62) | |
| Difference in proportion | 0.21 (0.15–0.26) | <0.0001 | |
| Odds ratio | 2.61 (1.97–3.46) | <0.0001 | |
| Positive predictive value | 0.95 (0.92–0.99) | 0.97 (0.95–1.00) | |
| Difference in positive predictive value | 0.02 (0.01–0.05) | 0.25 | |
| Odds ratio | 0.58 (0.22–1.55) | 0.27 | |
*
Values in parentheses are 95% CIs.