Representative GRP-R and PSMA immunohistochemistry with corresponding 68Ga-RM2 and 68Ga-PSMA-617 PET/CT images from 2 patients. (Top) Hematoxylin, eosin, and saffron staining of ISUP-2 sample (×5 magnification) with negative PSMA immunohistochemistry (×5 magnification), negative 68Ga-PSMA-617 PET/CT, positive GRP-R immunohistochemistry (×20 magnification), and positive 68Ga-RM2 PET/CT. (Bottom) Hematoxylin, eosin, and saffron staining of ISUP-5 sample (×5 magnification) with positive PSMA immunohistochemistry (×5 magnification), positive 68Ga-PSMA-617 PET/CT, negative GRP-R immunohistochemistry (×20 magnification), and negative 68Ga-RM2 PET/CT. HES = hematoxylin, eosin, and saffron; IHC = immunohistochemistry. Intensity-scale bars indicate SUV.