68Ga-RM2 maximum-intensity projection (A); 68Ga-PSMA-617 maximum-intensity projection (B); hematoxylin, eosin, and saffron staining of histologic slice from prostatectomy of patient 7 with manual demarcation of tumor lesions (C); 68Ga-RM2 transaxial PET/CT image (D); and 68Ga-PSMA-617 transaxial PET/CT image (E). Anterior ISUP-3 lesion and right basal ISUP-2 lesion were seen on histology, with 2 small lesions < 0.1 cm3 (C). 68Ga-RM2 PET/CT and 68Ga-PSMA-617 PET/CT showed similar uptake on ISUP-3 lesion: SUVmax was 6.7 for 68Ga-RM2 and 6.8 for 68Ga-PSMA-617 (arrowheads). 68Ga-RM2 was the only radiopharmaceutical able to detect ISUP-2 lesion well (arrows): SUVmax was 7.3 for 68Ga-RM2 and 3.4 for 68Ga-PSMA-617. HES = hematoxylin, eosin, and saffron.