Table 1.
Peptide transitions and corresponding isotope labels used for IMER-LC-MS/MS quantification of apolipoproteins.
| Protein | Peptide 1 | Peptide 2 | Peptide 3 |
|---|---|---|---|
| apoA-I | THLAPYSDE[L + 7]R(y8) | ATEHLST[L + 7]SEK(y6) | AKPALED[L + 7]R(y7) |
| apoA-II | EQLTPL[I + 7]K(y5) | - | |
| apoA-IV | LEPYADQL[L+7]R (y6) | LTPYADEF[K + 8] (y6) | - |
| apoB-100 | ATGVLYDY[V+6]NK (y6) | AAIQA[L + 7]R(y5) | TGISPLAL[I + 7]K(y6) |
| apoC-I | TPDVSSA[L + 7]DK(y8) | EWFSETFQ[K + 8] (y6) | - |
| apoC-II | TYLPA[V + 6]DEK(y7) | ESLSSYWESA[K + 8] (y7) | - |
| apoC-III | GWVTDGFSS[L + 7]K(y7) | DALSSVQESQVAQ[Q+ 7]AR (y8) | - |
| apoE | SELEEQLTP[V+6]AEETR (y7) | LQAEAF[Q+7]AR (y7) | - |