Table 4.
Parameter | No. of patients |
n (%) Accuracy (TP + TN) |
P* | |||
---|---|---|---|---|---|---|
| ||||||
Correct classification | Wrong classification | |||||
|
|
|||||
WD (TP) | Non-WD (TN) | WD (FP) | Non-WD (FN) | |||
Discriminant function (<−0.95) | 54 | 157 | 1 | 1 | 99.1 | <0.001 |
| ||||||
Caeruloplasmin (<0.14 g/L) | 54 | 154 | 4 | 1 | 97.7 | <0.001 |
| ||||||
Caeruloplasmin (<0.20 g/L) | 54 | 133 | 25 | 1 | 87.8 | <0.001 |
| ||||||
Total copper (<11 µmol/L) | 53 | 137 | 21 | 2 | 89.2 | <0.001 |
| ||||||
NCC1 (<1.6 µmol/L) | 38 | 133 | 25 | 17 | 80.3 | <0.001 |
| ||||||
NCC1 (<3.9 µmol/L) | 47 | 80 | 78 | 8 | 59.6 | <0.001 |
| ||||||
NCC% (<10%) | 26 | 134 | 24 | 29 | 75.1 | <0.001 |
| ||||||
NCC2 (<200 mcg/L) | 47 | 83 | 75 | 8 | 61.0 | <0.001 |
| ||||||
CCR (<8 µmol/g) | 31 | 96 | 62 | 24 | 59.6 | 0.027 |
*Based on Pearson’s chi-square test. Value is significant at 0.05. CCR: copper-caeruloplasmin ratio, FN: false negative, FP: false positive, NCC%: non-caeruloplasmin copper percentage, NCC1: non-caeruloplasmin copper in molar unit, NCC2: non-caeruloplasmin copper in mass unit, TN: true negative, TP: true positive, WD: Wilson disease