Skip to main content
. 2023 Mar 20;118:e220252. doi: 10.1590/0074-02760220252

TABLE. Overview of some neurodegenerative conditions.

NDs-types Main associated disease Neuropathologies Protein aggregates
Prion diseases Creutzfeldt-Jakob disease Spongiform changes PrP
Tauopathies Alzheimer’s disease Neuritic plaques neurofibrillary tangles Tau and Aβ
Pick’s disease Pick body Tau
Synucleinopathies Lewy body disorders Lewy bodies α-Synuclein
Parkinson’s disease Lewy neurites
Transactive response DNA-binding protein 43 (TDP-43) proteinopathies Amyotrophic lateral sclerosis Motor neuron loss TDP-43
Inclusion